Ellagic Acid: Exploring its potential in women healthcare

• Pragya Pandey,*  
• Shoebul Haque,  
• Farah Asif,  
• Rakesh Kumar Dixit

Abstract

LETTER TO EDITOR TITLE: Ellagic Acid: Exploring its potential in women healthcare Dear Editor, Greetings for the day. I have read the article titled “Investigation of effect of ellagic acid on premature ovarian insufficiency” published in your journal. I want to congratulate the authors for this successful original research article and make my contributions to it. Ellagic acid is a polyphenolic compound, chemically it is a dilactone of Hexahydroxy diphenic acid (HHDP). It is commonly found in fruits like pomegranate, raspberries etc.(1) Among its various properties includes Hypolipidemic actions, Hypoglycemic actions. It is also found to decrease the occurrence of Non-Alcoholic Fatty Liver Diseases. (2) It also has shown effect in preventing age related disorders like dementia.(3) Premature Ovarian insufficiency or failure is a prevalent disorder in developed as well as developing nations. It is defined as non-physiological amenorrhea in females before age of 40 but after puberty. As rightly stated by the authors, ellagic acid has shown potential in improving the Premature Ovarian insufficiency. I would like to add that ellagic acid has shown to be having effects on hair follicle regeneration as well as shown by previous studies.(4) It is observed to be showing effect on stimulation of hair regeneration in animal models of ferroptosis. It has also shown improvement in testosterone induced alopecia as well. Moreover, it has also shown improvement in the problem of graying of hair. (5) Adding to the author’s study, I wanted to convey that use of ellagic acid might also simultaneously aid in the hair loss associated disorders seen in patients of Premature Ovarian Failure / Insufficiency. In the conclusion, in developing nation like ours where healthcare is evolving at a rapid pace, having a single compound capable enough of addressing multiple associated disorders would be a boon. Premature Ovarian failure itself being a major load on women healthcare contributes to many associated disorders like anxiety and hair loss. In such scenario if proper research can be accumulated to address such issues simultaneously will be a major up roll in women healthcare. In the end, I would like to express my gratitude for allowing me to express my views on the related subject matter. Thanking you.

Keywords

Amenorrhea,Ellagic Acid,Healthcare,Primary Ovarian Insufficiency ,Women