Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Review Article
Author Details :
Volume : 6, Issue : 4, Year : 2019
Article Page : 107-112
https://doi.org/10.18231/j.ijpp.2019.024
Abstract
Liver act as metabolic factory of the body and metabolism of virtually every foreign substance. Its functioning is crucial for health and disease. Chemicals that cause liver injury are called hepatotoxicants. More than 950 drugs have been implicating in causing liver injury and were withdrawn from the market. Mechanism of hepatotoxicity induced by drug, immune based and genetic based toxicity. The drug models which are applied to study hepatotoxicity are Paracetamol, CCl4, Galactosamine, Alcohol, Azathioprine, Rantidine and different classof drugs cause acute and chronic liver injury.
Keywords: Hepatotoxicity, Hepatotoxicants, Mechanism, Liver injury, Drugs.
How to cite : Sonar N S, Nagalakshmi N C, Hemalatha S, Hariprasad Mg, Hepatotoxicity and hepatotoxicants: A systematic review. Indian J Pharm Pharmacol 2019;6(4):107-112
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