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To assess the rationality of pharmacotherapy of patient in clinical situations and validation of questionnaire tool used in rational pharmacotherapy

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Original Article

Author Details : Avinash Vikram Turankar*, Ashwita Uday Shetty, Pramoda N, Vijay Motiram Motghare, Chetan Shankarrao Urade

Volume : 7, Issue : 4, Year : 2020

Article Page : 251-255

https://doi.org/10.18231/j.ijpp.2020.042

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Abstract

Objectives: 1. To provide a structured tool to assess rationality based on the 10 domains of Rationality score; 2. To find out the impact of the structured tool for judging the rationality score of Pharmacotherapy in various clinical situations e.g. High, Moderate and Low rationality score.
Methodology: A rationality scale was developed to check the coefficient of variation in each parameter of
rationality, on a scale of 1 to 10, acronymed as R.A.T.I.O.N.A.L.I.T.Y.
Various clinical cases were discussed and treatment was criticised if any. These cases were then rated
according to the rationality scale.
High Rationality - Score > 6, Average Rationality – Score > 4 and < 6>< 4.
Results: For high rationality score, the top 5 parameter are availability of drugs, lab monitoring, rational
combination, Protocol/Regime and if objectives of treatment fulfilled.
For average rationality scores, the top 5 parameters are Objective of treatment, Availability of drugs,
Treatment correctness, lab monitoring and Protocol/Regime followed.
For low rationality, the lowermost 5 parameters were cost of therapy, irrational combination, lab monitoring, use of trade names instead of generic names and availability issues starting from the lowest.
Conclusion: Parameters like availability of the drugs, lab monitoring, presence or absence of irrational combinations are critical and common judgement parameters while judging if the therapy is rational or not.

Keywords: Rational pharmacotherapy, Rationality score, Questionnaire tool.

How to cite : Turankar A V , Shetty A U , Pramoda N, Motghare V M , Urade C S , To assess the rationality of pharmacotherapy of patient in clinical situations and validation of questionnaire tool used in rational pharmacotherapy. Indian J Pharm Pharmacol 2020;7(4):251-255

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