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Anticataract activity of pioglitazone by using in-Vitro goat lens model

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Original Article

Author Details : Rinkal R. Aware*, Hemant J. Pagar, Ganesh D. Barkade, Shweta Dhawane

Volume : 8, Issue : 3, Year : 2021

Article Page : 208-211

https://doi.org/10.18231/j.ijpp.2021.036

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Abstract

In the present study we have selected antioxidants agents like Pioglitazone and Ascorbic acid were subjected for anti-cataract activity by in vitro glucose induced cataract model. In the procedure, goat lenses was incubated along with the aqueous humor solution containing 55mM glucose with Enalpril as a standard compound and Pioglitazone with varied concentration for the time interval of 72 hours at room temperature. There was a formation of blur layer on the goat eyeball occurs after 10-12 hours and this process complete after 72 hours. The cataract inducing lenses showing higher level of Na, MDA (P<0>

Keywords: Anticataract, Antioxidants, Enalpril, Free radicals, In vitro, Pioglitazone

How to cite : Aware R R, Pagar H J, Barkade G D, Dhawane S, Anticataract activity of pioglitazone by using in-Vitro goat lens model. Indian J Pharm Pharmacol 2021;8(3):208-211

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