Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 9, Issue : 3, Year : 2022
Article Page : 180-186
https://doi.org/10.18231/j.ijpp.2022.032
Abstract
India witnessed a devastating second surge of COVID-19 cases from March 2021. Evidence strongly advocates its association with the patients’ age, gender, pre-existing comorbidity, vaccination status, and Remdesivir administration during the treatment of the disease. The objective of this study is to evaluate the significant relation of these five factors to in-hospital COVID-19 mortalities. We conducted a retrospective, cross-sectional, and observational cohort study between Jan 01 and May 30, 2021 in a tertiary care center in India. The outcome of interest is to identify the effect of vaccination, co-morbidities, and Remdesivir administration on COVID-19 mortality using SPSS software version 25.0 (IBM Corp., Armonk, NY, USA). The mortality rate was found to be 6.8 % (N=117) during hospitalization. The mean age of patients who died due to COVID-19 was 70.41 ± 15.04 years and the median was 68.34 (IQR: 59.61-83.38) years. About 89% of the population was over 55 years of age. The mortality rate was found to be higher in males (N=77; 65.8%). Out of 117 deaths, 95 patients (81.2%) were unvaccinated, whereas only 15.4% (N=18) and 3.4% (N=4) have taken a single and double dose respectively. Approximately, 3 quarter of patients had 1 or more comorbidity. Remdesivir administration is associated with the survival of 84.0% in moderate to severe COVID-19 infected patients. Results of our study coincide with the outcomes of studies done in the past concluding that age, gender, pre-existing comorbidities, vaccination status, and Remdesivir administration, these five factors are associated with COVID-19 mortalities.
Keywords: COVID19, Hospitalization, Mortality, Remdesivir, Second wave, SARSCoV2
How to cite : Pandey R, Mesharm A, Mortality analysis in cases of COVID-19 during the second wave at a tertiary care center in western India. Indian J Pharm Pharmacol 2022;9(3):180-186
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