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Prescribing pattern of antiepileptic drugs in tertiary care teaching hospital, Nagapattinam

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Original Article

Author Details : Lakshmi Sabapathi Sundaram*, Hathija Asika Nasurdeen, Jayalakshmi Subramaniyam, Krishna Sumathi Murugaiyan

Volume : 10, Issue : 1, Year : 2023

Article Page : 33-36

https://doi.org/10.18231/j.ijpp.2023.009

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Abstract

Background: Epilepsy is a chronic neurological disorder of brain cells. The older and newer antiepileptics are the mainstay of the treatment of epilepsy. The present study is to determine the prescription pattern of antiepileptic drugs.
Materials and Methods: An observational retrospective study, conducted at government district headquarters medical college, Nagapattinam. Data was collected for about 6 months from April 2021-September 2021.100 patients were included in this study based on inclusion and exclusion criteria.
Result: In 100 patients 68% accounted male and 32% accounted female. The most common type of seizure has been identified as generalized seizure (54%) followed by secondary seizure (23%) and other types. Phenytoin accounted for 69 %. Among the different classifications of antiepileptic drugs benzodiazepines (50.6%) was the commonly prescribed classification of AED. Older agents accounted almost 98% and only 2% of drugs from newer agents. TheMonotherapy has been noted only 19%.
Conclusion: In this study we identified, combinational therapy has been mostly prescribed. Benzodiazepines were commonly prescribed class of agent. Phenytoin was mostly prescribed drug. Most patients have received older anti-epileptics agents.

Keywords: Epilepsy, Antiepileptic drugs (AED'S), Monotherapy, Combinational therapy, Prescribing pattern

How to cite : Sundaram L S, Nasurdeen H A, Subramaniyam J, Murugaiyan K S, Prescribing pattern of antiepileptic drugs in tertiary care teaching hospital, Nagapattinam. Indian J Pharm Pharmacol 2023;10(1):33-36

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