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Ivabradine: Unraveling the intricacies of heart rate modulation in cardiovascular pathologies

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Review Article

Author Details : Geeta Y Gupta*, Yogesh A Gupta

Volume : 10, Issue : 4, Year : 2023

Article Page : 260-264

https://doi.org/10.18231/j.ijpp.2023.045

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Abstract

Cardiac dysregulation, specifically perturbations in heart rate constitutes a pivotal factor influencing the morbidity and mortality associated with diverse pathological conditions including angina (chronic/stable), acute coronary syndrome, heart failure, renal failure, respiratory distress, chronic obstructive pulmonary disease, multiorgan dysfunction syndrome, mitral valve prolapse, and mitral stenosis. The pharmacological apparatus for heart rate control refined over decades encompasses various classes of agents each adhering to specific protocols. Among these Ivabradine has garnered attention as a non-inferior alternative to extant heart rate-reducing medications providing a subtle approach to cardiovascular therapeutics.

Keywords: Ivabradine, I funny (I f ) channel, HCN Channel Blockers, Chronic stable angina, Acute coronary syndrome, Chronic heart failure, Multiorgan dysfunction syndrome, Cardiotonic drugs

How to cite : Gupta G Y, Gupta Y A, Ivabradine: Unraveling the intricacies of heart rate modulation in cardiovascular pathologies. Indian J Pharm Pharmacol 2023;10(4):260-264

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