Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 3, Issue : 2, Year : 2016
Article Page : 49-51
Abstract
Background: Vitamin D3 has been linked to everything as cancer, diabetes mellitus heart disease etc. One important function of vitamin D is on the beta cells of pancreas that secretes insulin. In cases of deficiency of vitamin D there is not only a decreased secretion of insulin but also increased insulin resistance as proved by various studies. Studies have also shown that treatment of vitamin D deficiency delays the development of insulin resistance & so diabetes mellitus.
Methods: Our objective was to examine the association of serum 25-hydroxyvitamin D levels with type 2 diabetes mellitus & effects of vitamin D on it. Analysis were carried out on 200 patients (120 men & 80 women) aged about 35 or above conducted for 1 year in 2014. Diabetes mellitus was defined as fasting plasma glucose > 126mg% or current use of oral hypoglycaemic agents or insulin.
Results: Compared to individuals with a sufficient serum 25(OH)D concentration >75nmol/L, the observed values are divided into 4 groups severe (<25nmol/L), mild (25 to <50 nmol/L), moderate (50 to<75nmol/L) & normal >75nmol/L. The enrolled patients were investigated for blood sugars, vitamin D levels, lipid profiles & HbA1C status at baseline & at the end of 1 year.
Conclusion: Correction of vitamin D deficiency postpones the development of insulin resistance & thus diabetes mellitus & also improves glycemic control.
Keywords: Vitamin D, Type 2 Diabetes Mellitus, Insulin resistance, HbA1C
How to cite : Kumari S, Upadhyay M K, Deo A K, Role of vitamin D on blood sugar level in diabetic patients. Indian J Pharm Pharmacol 2016;3(2):49-51
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