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A comparative analysis of Asian medicinal herbs Catharanthus roseus and Vinca alba based on their antidiabetic, anticancer and turbidimetric antibiotic efficacies

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Original Article

Author Details : Debaleena Samanta, Malavika Bhattacharya*

Volume : 11, Issue : 4, Year : 2024

Article Page : 195-204

https://doi.org/10.18231/j.ijpp.2024.033

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Abstract

Background: Being on Northern Hemisphere, India is a geographically established country with a large variety of species variation in terms of animals and plants species. According to geographical location, the land barriers in north and the oceanic barriers in east and west region of India made the differences among medicinal plant species being isolated from different areas.
Aim: To isolate the pharmaceutical values of those species for antidiabetic, anticancer and antibiotic potencies are essential for further drug establishments from Catharanthus roseus and .
ethods: Turbidimetric Assay or Tube Assay method is used to determine antibiotic efficacy against Vinblastine (VLB) and Vincristine (VCR) Reference standards. Bradford assay is used to identify protein content against standard curve. Polysaccharide and Amino acid assay are used to evaluate unknown concentration of dextrose and glycine against known concentration. Presence of alkaloids are tested by Mayer’s test. Thin Layer Chromatography is used to assume presence of Amino acids rich in anticancer peptides.
Result: Both leaf and stem extracts of and are showing significant amount of polysaccharide content, strong protein content, presence of alkaloids, anticancer peptides, hypoglycemic or antidiabetic and antibiotic efficacies.
Conclusion: The medicinal plant species and are well known to be helpful for the medical, biological, pharmacological and biochemical studies for human benefits. So, the desire of medicinal plant utility is a certain thing from the ancient era, till from “Ayurveda shastra” that intricates the therapeutic capability of and.

Keywords : Madagascar periwinkle, Antibiotic, Antidiabetic, Anticancer, Vinblastine (VLB), Vincristine (VCR), Turbidimetric assay

How to cite : Samanta D, Bhattacharya M, A comparative analysis of Asian medicinal herbs Catharanthus roseus and Vinca alba based on their antidiabetic, anticancer and turbidimetric antibiotic efficacies. Indian J Pharm Pharmacol 2024;11(4):195-204

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