Withaniacoagulans: Bridging tradition and therapeutic

• Author Details:   
• Shivshankar M Gunjegaonka ^*
• Vaishnavi Vijay Pawar
• Shreya Basweshwar Mathpati
• Sohail Allibaba Shaikh
• Sanyukta Kakasaheb Salunke
• Geeta N Sapkale

Withania coagulans have significant medicinal properties, well-proven therapeutic effects and a lack of side effects. It is commonly known as an Indian cheese maker, Indian rennet, Panir ke phool, or Panner Doda.It is a member of the Solanaceae family. Withania coagulans is a gray-whitish shrub east of the Mediterranean region extending to South Asia. Withaniacoagulans are geographically distributed in the various areas of India, Iran, Afghanistan, Pakistan, and Nepal. Withaniacoagulans are mainly used in multiple Ayurvedic preparations. The main chemical constituent of Withaniacoagulans is Withanolide. Withanolide is primarily classified into seven groups that is Withanolide glycoside, Withathysalin, Thysalin, Nicadrenons, Withajardine, Terculactones, and Acnistins. Withaniacoagulans exhibit Hypoglycemic, Hypolipidemic, Anti-Inflammatory, Anti-microbial, Anti-Bacterial, Immunosuppressive, Hepatoprotective, Anti-Tumour, Anti-oxidant, and diuretic properties. The leaves of Withania coagulans consist of Withaferin that possesses Anti-cancer activity. Various marketed preparations of Withania coagulans are available. The fruits of Withaniacoagulans have sedative activity.

Keywords: Withania coagulans, Hypoglycemic activity, Hypolipidemic activity, Anti-inflammatory, Anti-microbial, Anti-tumor