Indian Journal of Pharmacy and Pharmacology

Print ISSN: 2393-9079

Online ISSN: 2393-9087

CODEN : IJPPTK

Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...

Article type

Case Report


Article page

227-228


Authors Details

Jitendra Singh, Kamlesh K Gupta, Anju Dinkar, Virendra Atam, Ravi Mishra


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Steven-Johnson Syndrome following Sodium Valproate Monotherapy


Case Report

Author Details : Jitendra Singh, Kamlesh K Gupta, Anju Dinkar, Virendra Atam, Ravi Mishra

Volume : 3, Issue : 4, Year : 2016

Article Page : 227-228


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Abstract

Steven-Johnson Syndrome (SJS) is a severe, episodic, acute mucocutaneous reaction characterized by blisters and epidermal detachment resulting from epidermal necrosis in the absence of substantial dermal inflammation. We report a case of 64-year old male farmer who developed Stevens-Johnson syndrome following the ingestion of Sodium Valproate monotherapy prescribed for seizure disorder. He was treated with intravenous corticosteroids, antihistamine, antibiotics and supportive therapy. We are presenting this case to highlight the serious adverse effect of commonly prescribed antiepileptic drug, sodium valproate as a monotherapy.

Keywords: Sodium Valproate, Steven-Johnson Syndrome, Seizure Disorder, Mucocutaneous reaction, Corticosteroid


How to cite : Singh J, Gupta K K, Dinkar A, Atam V, Mishra R, Steven-Johnson Syndrome following Sodium Valproate Monotherapy. Indian J Pharm Pharmacol 2016;3(4):227-228

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