Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 4, Issue : 2, Year : 2017
Article Page : 69-71
Abstract
Introduction: Esophageal carcinoma (EC) ranks 6th among all cancers in mortality. Gastric carcinoma (GC) is the 2nd most common cancer among men and 3rd most among females in Asia and worldwide. The aetiology in majority of patients was linked to tobacco and alcohol. Usually, treatment regimen followed EC, GEJ (gastroesophageal junction) and gastric carcinoma is DCF regimen as per National Comprehensive Cancer Network guidelines.
Objectives: To study the prescribing pattern in esophageal cancer, GEJ cancer & gastric carcinoma in a tertiary care hospital.
Materials and Method: A prospective observational study was done for a period of 6 months in both male & female patients diagnosed with EC, GEJ & GC. Prescribing patterns were recorded & analysed.
Results and Discussion: Total of 31 patients was included in the study; of which 19, 9 & 3 were diagnosed as EC, GC and GEJ carcinoma respectively. The most common treatment regimen followed were combination of cisplatin+5 fluorouracil+ radiotherapy in EC & GEJ whereas oxaliplatin +5-fluorouracil + leucovorin in GC.
Conclusion: In our study, anticancer drugs were prescribed in a combination therapy. In majority of upper gastrointestinal carcinoma patients 5-FU and platinum based combination therapy were used. Dexamethasone, granisetron and ondensetron were used to treat adverse drug reactions of anticancer drugs.
Keywords: Esophageal carcinoma; Gastric Carcinoma; GEJ carcinoma
How to cite : Annapurna V, Anuradha H, Shivamurthy M, Study of prescribing pattern in patients with gastro-oesophageal carcinoma in a tertiary care hospital. Indian J Pharm Pharmacol 2017;4(2):69-71
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