---

Prescription pattern of anti-epileptic medications in a tertiary care centre

---

Original Article

Author Details : Shilpa B. N., Sushma H. K., Latha S., Shashikala G. H.

Volume : 5, Issue : 1, Year : 2018

Article Page : 7-10

https://doi.org/10.18231/2393-9087.2018.0003

Suggest article by email

Get Permission

---

Abstract

Introduction: The objective of this study was to study the prescribing pattern of antiepileptic medications in patients with epilepsy in a tertiary care hospital.
Materials and Methods: This was an observational study, conducted in psychiatry outpatient department (OPD) of Bapuji attached to Jagadguru Jayadeva Murugarajendra medical college and CG Hospital, Davangere. Patients demographic details, clinical diagnosis, type of epilepsy, type of AED used, drug dose and frequency of 100 outpatients who attended the psychiatry OPD was recorded.
Results: A total of 100 prescriptions were analysed with more number of males (62%) than females (38%). Epilepsy was more commonly seen in the patients of age group of 20-40 years (52%) and GTCS was diagnosed in 79% of the patients followed by partial seizures and other types. Majority of them received monotherapy (67%) with most commonly prescribed AED phenobarbitone (28%) followed by phenytoin (16%), levetiracetam (12%), carbamazepine (8%), lorazepam (2%) and ethosuximide (1%). 33% of the patients received combined therapy, most commonly used two drug combination was phenobarbitone with phenytoin and three drug combination was with phenobarbitone, phenytoin and carbamazepine. 19 patients reported adverse events, most common were related to CNS.
Conclusion: In our study, majority of the patients were males with age group 20-40 yrs and most commonly used drugs were conventional AEDs as monotherapy with phenobarbitone, phenytoin and levetiracetam.

Keywords: Epilepsy, Anti Epileptic Drug (AED), Monotherapy, Combined therapy, Prescribing pattern.

 

How to cite : Shilpa B. N., Sushma H. K., Latha S., Shashikala G. H., Prescription pattern of anti-epileptic medications in a tertiary care centre. Indian J Pharm Pharmacol 2018;5(1):7-10

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.