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PHARMACOVIGILANCE STUDY IN CASES OF BRONCHIAL ASTHMA IN TERTIARY CARE HOSPITALS OF EASTERN INDIA

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Original Article

Author Details : Shambo Samrat Samajdar, Parbaty Panda, Saumyajit Maiti, Anju Prasad, Chaitali Pattanayak, Kamal Loch

Volume : 2, Issue : 2, Year : 2015

Article Page : 85-89

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Abstract

Background & Objective: Bronchial asthma, a common chronic disease affecting 300 millions of people across the world. The number of patients suffering is increasing day by day. This study was conducted to evaluate adverse drug reactions in asthma patients attending outpatient department of Hi-Tech Medical College & Hospital, Bhubaneswar & Allergy & Asthma clinic Moulali, Kolkata.

Methodology: 200asthmatic patients irrespective of age and sex on anti-asthmatic drugs were surveyed during the time period of September 2013 to August 2014.CDSCO ADR reporting forms were filled. Naranjo’s adverse drug reaction probability scale was used to know the causality of the adverse drug reactions.

Result: Among the 200 patients on anti-asthmatic drugs, 20 patients presented with 38 types of adverse drug reactions. Oral thrush was the most common adverse drug reaction (31.58%) among all ADRs followed by palpitation(13.6%),running nose & sore throat(both 10.53%), tremor (7.9%) , dizziness & dry cough(both 5.26%),skin rashes, hepatitis, headache, loose motion, constipation, drowsiness(each 2.63%) in patients treating with inhalational corticosteroids, montelukast, long acting beta2 sympathomimetics like indicaterol, salmeterol sublingual allergen immunotherapy & theophylline.

Conclusion: This study reveals the importance of ADR monitoring in patients receiving drug therapy for asthma. Larger sample size with long duration of study is needed to get better result.

How to cite : Samajdar S S, Panda P, Maiti S, Prasad A, Pattanayak C, Loch K, PHARMACOVIGILANCE STUDY IN CASES OF BRONCHIAL ASTHMA IN TERTIARY CARE HOSPITALS OF EASTERN INDIA. Indian J Pharm Pharmacol 2015;2(2):85-89

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