Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 2, Issue : 2, Year : 2015
Article Page : 100-104
Abstract
A simple, sensitive and reproducible UV Spectroscopic method was developed for the quantitative determination of Tramadol Hydrochloride. The ?max of the tramadol hydrochloride was observed and recorded to be 271.00nm in distilled water as well as in the phosphate buffer pH 6.8 and it complies with the requirement of the standard texts. Correlation coefficientR?2;in distilled water was 0.998 and of buffer solution was found as 0.997.The method was validated as per ICH Q2 (R1) guidelines and confirmed a good performance complies with respect to linearity, accuracy, and precision, range limit of detection and limit of quantification. So the proposed method can be used in routine quality control laboratories.
How to cite : Kamble R K, Chauhan C S, Kamble P R, ANALYTICAL METHOD DEVELOPMENT AND VALIDATION STUDIES OF TRAMADOL HYDROCHLORIDE. Indian J Pharm Pharmacol 2015;2(2):100-104
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