Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 5, Issue : 3, Year : 2018
Article Page : 129-134
https://doi.org/10.18231/2393-9087.2018.0028
Abstract
Introduction: To know the Neuropharmacological effects of Albizzia chinensis extract in rats and mice.
Materials and Methods: The test compound was evaluated experimentally for its neuropharmacological activities in rats and mice. Blind neuropharmacological screening, potentiation of barbiturate hypnosis, stimulation of the central nervous system, maximal electroshock and pentylenetetrazol induced convulsions, analgesic activity were studied.
Results: The compound potentiated pentobarbital hypnosis, reduced spontaneous motor activity, antagonized amphetamine induced hyperactivity, blocked the conditioned avoidance response without affecting the unconditioned response and showed analgesic activity by the tail-flick method but not in hot plate model in the experimental animals.
Conclusion: The compound is similar to chlorpromazine and morphine.
Keyword: Saponin, Central nervous system, Animals.
How to cite : Gupta N, Kansal D, Neuropharmacological effects of Albizzia Chinensis extract. Indian J Pharm Pharmacol 2018;5(3):129-134
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