Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 6, Issue : 1, Year : 2019
Article Page : 11-13
https://doi.org/10.18231/2393-9087.2019.0003
Abstract
Introduction: Few of the antihypertensive medicine have been withdrawn owing ADRs. Some are serious enough leading to hospitalization or withdrawal of treatment.
Objective: To study the tolerability of Cilnidipine and Amlodipine in patients of hypertensive.
Materials and Methods: This study was a collaboration between department of Pharmacology and Medicine of Bidar Institute of Medical Sciences (BRIMS), Bidar. Duration of study was for 9 months from May 2018- January 2019. 100 newly diagnosed mild and moderate hypertensive patients of either sex aged between 18-60yrs were included. ADR were noted and compared using parametric test. Significance was defined as P < 0>
Result: The patients mean age receiving Cilnidipine was 42.98 ± 8.35 and Amlodipine was 44.48 ± 9.03. On comparison of ADRs between Cilnidipine and Amlodipine it is clear that Amlodipine has more ADRs than Cilnidipine. The Comparison of pedal edema between both the groups show a Statistical Significance with p= 0.0003.
Conclusion: It can be concluded from our study that Cilnidipine seems to be better than Amlodipine in the management of the hypertensive patients.
Keywords: ADRs, Cilnidipine, Amlodipine, Antihypertensive drugs.
How to cite : Dharpur P M, V.c K, A study at BRIMS hospital for comparing the tolerability of Cilnidipine and Amlodipine in the treatment of hypertension. Indian J Pharm Pharmacol 2019;6(1):11-13
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