Indian Journal of Pharmacy and Pharmacology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2393-9079
Online ISSN: 2393-9087
CODEN : IJPPTK
Indian Journal of Pharmacy and Pharmacology (IJPP) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award programs. With more...Original Article
Author Details :
Volume : 6, Issue : 2, Year : 2019
Article Page : 42-44
https://doi.org/10.18231/j.ijpp.2019.010
Abstract
Introduction: ADRs are one of the major causative factors for increased morbidity and mortality rate in human healthcare. Monitoring adverse drug reaction in tuberculosis patients is not done properly by the healthcare professionals owing to lack of awareness.
Materials and Methods: About 100 TB diagnosed patients were selected for the study at Bidar Institute of Medical sciences. Based on the prospective observational study method the cases were divided into before and after anti-TB therapy under DOTS course. Several lab examinations were conducted for the patients after the treatment. The severity of ADRs were recorded.
Results: After the study we observed about 57% of mild ADR, 31% of moderate ADR and 12% severe ADRs were noted in the patients who are under DOTS therapy in RNTCP unit. The results obtained from this study showed that when compared to female patients, ADRs faced by male patients are of high percentage.
Conclusions: There is increasing evidence from preclinical and clinical studies supporting the adverse effects of anti-TB therapy, but further mechanistic and experimental studies are required to establish the dose–response relationships and safety profiles of these kind of therapeutic medicines.
Keywords: Adverse drug reactions, DOTS, Tuberculosis, Pharmacovigilance.
How to cite : Pasha S S, Sabiha N, Naseeruddin S, Adverse drug reactions impact on DOTS therapy courses in tuberculosis patients at bidar institute of medical sciences. Indian J Pharm Pharmacol 2019;6(2):42-44
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