---

Study of invitro thrombolytic activity of different extracts of Syzygium cumini

---

Original Article

Author Details : Kalyan Ranjan Dash, Jagan Kumar Das*, Amiya Kumar Prusty

Volume : 6, Issue : 3, Year : 2019

Article Page : 79-82

https://doi.org/10.18231/j.ijpp.2019.018

Suggest article by email

Get Permission

---

Abstract

The present study was carried out to investigate the invitro thrombolytic activity of leaf and seed extracts of Syzygium cumini. The thrombolytic activity of different concentration of extracts was compared with the standard drug Streptokinase. The blood collected from human volunteers was taken as test sample for carrying out thrombolytic activity. 800ug/ml leaf extracts of Syzygium cumini showed the mean % of clot lysis as 57.07%+/-0.76, 71.42%+/-0.75 & 86.99%+/-1.33 after incubation for 24hrs, 48hrs, and 72hrs respectively at 37?C. 800ug/ml seed extracts of Syzygium cumini showed the mean % of clot lysis as 44.93%+/-2.49, 66.58%+/-1.41, & 83.32%+/-2.27 after incubation for 24hrs, 48hrs, and 72hrs respectively at 37?C. The mean % clot lysis for the standard drug streptokinase was found to be 75.81% +/-0.71, 88.54%+/-1.02, and 93.04%+/-3.69 after incubation for 24hrs, 48hrs, and 72hrs respectively at 37?C.

Keywords: Aqueous extract, Syzygium cumini, Control, Streptokinase, In-vitro thrombolytic activity.

How to cite : Dash K R, Das J K, Prusty A K, Study of invitro thrombolytic activity of different extracts of Syzygium cumini. Indian J Pharm Pharmacol 2019;6(3):79-82

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.