The Potential of Ellagic Acid
Dear Editor,
I have read the article titled “Investigation of effect of ellagic acid on premature ovarian insufficiency” published in your journal. I want to congratulate the authors for this successful original research article and make my contributions to it.
Ellagic acid is a polyphenolic compound; chemically, it is a dilactone of hexahydroxy diphenic acid (HHDP). It is commonly found in fruits like pomegranates, raspberries, etc.1
Among its various properties are hypolipidemic and hypoglycemic actions. It is also found to decrease the occurrence of non-alcoholic fatty liver diseases.2 Click or tap here to enter text. It also has shown an effect in preventing age-related disorders like dementia.3
Premature ovarian insufficiency or failure is a prevalent disorder in developed as well as developing nations. It is defined as non-physiological amenorrhea in females before the age of 40 but after puberty.
As rightly stated by the authors, ellagic acid has shown the potential to improve premature ovarian insufficiency. I would like to add that ellagic acid has been shown to have effects on hair follicle regeneration, as well as shown by previous studies.4
It is observed to show an effect on the stimulation of hair regeneration in animal models of ferroptosis. It has also shown improvement in testosterone-induced alopecia as well. Moreover, it has also shown improvement in the problem of graying of hair.5
Adding to the author's study, I wanted to convey that use of ellagic acid might also simultaneously aid in the hair loss associated disorders seen in patients of premature ovarian failure/insufficiency.
In conclusion, in a developing nation like ours, where healthcare is evolving at a rapid pace, having a single compound capable enough of addressing multiple associated disorders would be a boon. Premature ovarian failure itself, being a major load on women's healthcare, contributes to many associated disorders like anxiety and hair loss. In such a scenario, if proper research can be accumulated to address such issues simultaneously, it will play a major role in women's healthcare.
In the end, I would like to express my gratitude for allowing me to express my views on the related subject matter.
